Ingredients
The main ingredient is Captopril


Character
White or off white tablets, or sugar coated tablets or film coated tablets, appear white or off white after removing the coating.
Indication
1. Hypertension; 2. Heart failure.
Specifications
12.5mg; 25g
Usage and dosage
Depending on the condition or individual differences. This product should be taken under the guidance or supervision of a physician, and the dosage should follow the principle of individualization and be adjusted according to the efficacy.
1. Common usage for adults
(1) Hypertension, take 12.5mg orally once, 2-3 times a day, and increase to 50mg within 1-2 weeks as needed, 2-3 times a day. If the efficacy is still unsatisfactory, other antihypertensive drugs can be added.
(2) Heart failure, starting with oral administration of 12.5mg 2-3 times a day, gradually increasing to 50mg 2-3 times a day if necessary. If further dosage is needed, it is recommended to observe the therapeutic effect for 2 weeks before considering; For patients who have recently taken a large amount of diuretics, are in a state of low sodium/low blood volume, and have normal or low blood pressure, the initial dose should be 6.25mg, three times a day, and gradually increased to the regular dose through testing.
2. Common dosage for children
To reduce blood pressure and treat heart failure, start with 0.3mg/kg of body weight three times a day, and if necessary, increase by 0.3mg/kg every 8-24 hours to obtain the minimum effective dose.
Taboo
Individuals allergic to this product or other angiotensin-converting enzyme inhibitors are prohibited from using it.
Pharmacology and Toxicology
This product is a competitive angiotensin converting enzyme inhibitor, which can not convert angiotensin I into angiotensin II, thus reducing peripheral vascular resistance, and reducing water and sodium retention by inhibiting aldosterone secretion. This product can also dilate peripheral blood vessels by interfering with the degradation of bradykinin. For patients with heart failure, this product can also reduce pulmonary capillary wedge pressure and pulmonary vascular resistance, increase cardiac output and exercise tolerance time.
Storage
Protect from light and store in a sealed container.
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