Ingredients
Metformin and Glipizide tablets are compound preparations, consisting of 250mg of metformin hydrochloride and 2.5mg of glipizide per tablet.
Character
This product is a film coated tablet, which appears white or off white after removing the coating.
Indication
This product is used for the initial treatment of type 2 diabetes, and is used to improve type 2 diabetes that can not fully control blood sugar by taking diet and exercise therapy alone.
Specifications
Metformin hydrochloride 250mg, glipizide 2.5mg
Adverse reactions
More than 5% of clinical adverse reactions include upper respiratory tract infections, diarrhea, dizziness, hypertension, nausea, and vomiting. hypoglycemia.
In a controlled clinical trial using metformin and glipizide tablets 250mg/2.5mg and 500mg/2.5mg, the number of patients with hypoglycemic symptoms (such as dizziness, trembling, sweating, hunger, etc.) and finger blood glucose measurement consumption results ≤ 50mg/dl were recorded as follows: 5 cases (2.9%) of glipizide, 0 cases (0%) of metformin, 13 cases (7.6%) of metformin and glipizide 250mg/2.5mg, and 16 cases (9.3%) of metformin and glipizide 500mg/2.5mg, respectively.
Taboo
Metformin and glipizide tablets are contraindicated in the following patients:
1. Patients with kidney disease or renal insufficiency caused by cardiovascular failure (shock), acute myocardial infarction, and sepsis (such as male serum creatinine levels ≥ 1.5mg/dl, female serum creatinine levels ≥ 1.4mg/dl, or abnormal creatinine clearance).
2. Patients with congestive heart failure who require treatment.
3. Patients allergic to glipizide or metformin hydrochloride.
4. Acute and chronic metabolic acidosis, including diabetes ketoacidosis patients, with or without coma symptoms. Diabetes ketoacidosis must be treated with insulin.
5. Patients receiving iodic acid salt control in the blood vessels for radiation studies should temporarily suspend the use of metformin and glipizide tablets, as these products may cause acute renal function changes.
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