Sigliptin and metformin tablets can directly attack the three major defects of type 2 diabetes - insulin deficiency, insulin resistance and liver glucose overproduction caused by damaged islets, providing an optimized treatment option for patients.
Ingredients
This product is a compound preparation, consisting of sitagliptin phosphate and metformin hydrochloride.
Indications
This product is a combination of two hypoglycemic drugs with complementary mechanisms to improve the blood sugar control of patients with type 2 diabetes: Sigliptin phosphate in the drug component is a dipeptidyl peptidase 4 (DPP-4) inhibitor, while metformin hydrochloride is a biguanide hypoglycemic drug.
This product, combined with diet and exercise therapy, is used for type 2 diabetes patients who still have poor blood glucose control after metformin monotherapy or are receiving combined treatment of the two.
Usage and dosage
General suggestion:
When using this product for hypoglycemic treatment, individualized doses should be given based on the patient's current treatment plan, treatment effectiveness, and drug tolerance, but should not exceed the maximum recommended daily dose of sitagliptin phosphate 100 mg and metformin 2000 mg.
The usual administration method is twice a day, taking medication with meals, and gradually increasing the dosage to reduce the gastrointestinal side effects associated with metformin.
Recommended dosage:
Determine the initial dose of this product based on the patient's current treatment plan. Take the medicine twice a day with meals. The available drug doses are:
50mg sitagliptin/500mg metformin hydrochloride
50mg sitagliptin/850mg metformin hydrochloride
For patients with poor blood glucose control when taking metformin alone:
The initial dose of this product should provide a dose of sitagliptin of 50mg twice daily (total daily dose of 100mg) plus the dose of metformin currently being taken.
For patients who are currently receiving treatment with both sitagliptin and metformin and need to switch treatment plans:
The initial dose of this product can be selected based on the dosage of sitagliptin and metformin currently being taken by the patient.
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